Only mammals can carry rabies. Traditionally, in Colorado, bats were the main source of rabies infections; however, in recent years the number of skunks testing positive for rabies has been rapidly increasing. Skunks now are the main source for rabies in Colorado. Other mammals can be infected with rabies from bats and skunks. Domestic animals such as dogs, cats, cattle, and horses can become infected by being bitten by a rabid wild animal.